Market Overview

Global High Throughput Screening Market size was valued at USD 22.31 Billion in 2023 and is poised to grow from USD 25.01 Billion in 2024 to USD 62.37 Billion by 2032, growing at a CAGR of 12.1% in the forecast period (2024-2032).

The Global High Throughput Screening (HTS) Market is the use of automated technology to conduct an unimaginable amount of chemical, biological, or pharmacological experiments simultaneously. Through this process, scientists are able to screen compound libraries in a highly efficient and cost-effective manner. HTS plays a vital role in drug discovery, particularly in the detection of potential drug candidates and disease biomarkers. It employs robots, liquid handling systems, and sophisticated data analysis software to enable thousands to millions of tests in a matter of time. HTS has numerous applications ranging from basic research to advanced ones like toxicity testing, disease modelling, and therapeutic discovery.

The market has expanded significantly with increasing demands for quick and effective drug discovery and development processes, with support from increasing disease burdens for diseases such as cancer, cardiovascular diseases, and neurodegenerative diseases. Pharmaceutical and biotechnology companies are embracing HTS as a way of fast-tracking drug development, minimizing costs, and maximizing opportunities for success. Besides, the personalized medicine has increased the need for HTS because the process has the capability to identify people who can be cured by individualized therapy, thereby highly relevant in precision medicine.

HTS is a key role throughout all stages of drug discovery, from target discovery, hit discovery, lead optimization, to preclinical development. HTS provides a convenient platform for the identification of hits of lead drug potential through its ability to allow large sets of chemicals or genetic libraries to be screened against target proteins in parallel. This rapidly propels forward lead optimization, which involves structurally differentiating hits found to make them optimal for activity and minimized in toxicity.

Furthermore, the incorporation of emerging technologies such as artificial intelligence, machine learning, and bioinformatics into HTS platforms is transforming the drug discovery model. The technologies discussed above improve upon the processing of gigantic amounts of data generated in screens to make the outcomes more accurate and predictive in nature. In addition, enhanced collaboration between drug companies, research institutions, and academic research organizations has also contributed to the dissemination of HTS technologies, providing valuable insights into polyfactorial diseases and driving drug development innovation.

HTS is also a central element involved in the determination of cellular response as well as gene function process and therefore constitutes the central application in systems biology. With the ability to examine thousands of biological samples as well as compounds within minutes, HTS is able to be used in identifying new biomolecules and therapeutic targets and hence the discovery of new drugs. The market will expand further as advances in technology and science make possible new fields of application of HTS, particularly in personalized medicine and precision therapeutics.

Market Drivers

Rising Prevalence of Chronic Diseases and Complex Disorders

• The increase in the incidence of chronic diseases and complex diseases is one of the key drivers of growth for the Global High Throughput Screening (HTS) Market. Some of the chronic diseases that have increased more rapidly across the world include heart disease, diabetes, cancer, and neurological disorders, resulting in increased demand for efficient and effective drug discovery platforms. The disorders are chronic in nature and entail sophisticated therapies, which encourages drug makers and healthcare professionals to explore alternative treatment options. HTS, with the ability to rapidly and efficiently screen enormous libraries of compounds, plays a central role in the identification of potential drug candidates that will treat such disorders.
• Most chronic diseases and multi-factorial disorders, like Alzheimer's disease or autoimmune diseases, have several biological pathways involved, and therefore are hard to be treated with conventional approaches. HTS facilitates the identification and validation of new targets and biomarkers that otherwise would not have been an option. HTS speeds up the process of finding successful treatments by allowing for the quick testing of thousands of chemicals or genetic molecules against the complex targets. The imperative for precision and personalized medicine that treats patients as individuals with treatments that are derived from their specific genetic profiles and disease states again underlines the significance of HTS in generating new therapies. With the weight of these conditions mounting, only demand for cutting-edge drug discovery technologies such as HTS will escalate.

Key Findings:

• In October 2023, Revvity Inc. (US) developed mass spectrometry solutions for newborn screening with SCIEX, a Danaher Corporation (US) subsidiary.
• In May 2024, Bio-Rad Laboratories, Inc. (US) introduced three new StarBright Red Dyes, StarBright Red 715, 775, and 815, that provide additional options and flexibility in standard and full-spectrum multicolour flow cytometry panels.

Growth in Personalized Medicine and Precision Therapeutics

• Increased personalized medicine and precision therapeutics is one of the major drivers for the Global High Throughput Screening (HTS) Market's growth. Personalized medicine is about customized medical treatments tailored to the unique aspects of each patient, such as their environment, lifestyle, and genetic background. As the medical field becomes more individualized in its treatment strategies, there is an increasing need for sophisticated technologies that can effectively determine the most effective treatments for certain groups of patients. HTS is at the centre of this shift by allowing rapid screening of large libraries of compounds against a broad set of genetic targets, thereby highlighting potential drug candidates most likely to be therapeutic for certain subgroups of patients.
• Precision medicines in their attempts to tailor therapy based on an individual's genotype have a tendency to require deep understanding of advanced disease mechanisms and the biological determinants of disease. HTS allows researchers to probe these mechanisms at high-throughput levels by screening thousands of compounds for binding and modulation activity against specific genetic or molecular targets. This integration of HTS with genomic research simplifies the identification of possible treatments for diseases such as cancer, neurological disorders, and genetic diseases. Increased use of personalized medicine is expected to fuel the demand for HTS technologies, driving innovations and advancements in drug discovery and development.

Key Findings:

• An important Memorandum of Intent was inked on November 8, 2023, in The Hague between India and the Netherlands with the view to increasing collaboration on the regulation of medical products and improving the quality of healthcare services for both countries.

Market Opportunities

Expanding Applications in Genomics and Biomarker Discovery

• Increasing uses in genomics and biomarker identification are critical in driving the Global High Throughput Screening (HTS) Market's growth. Genomics, the study of genes and their activity, has revolutionized with next-generation sequencing technology. HTS platforms are increasingly used in genomics research to analyse humongous genetic information rapidly and efficiently. With the capability to undertake high-throughput analysis of gene function, expression, and variation, HTS enables researchers to discover new genetic targets and mutations for disease, such as cancer, neurological disease, and genetic disease.
• Demand for HTS is being driven by the increased emphasis on biomarker discovery. Biomarkers, or biological indicators of disease or drug response, are increasingly contributing to diagnosis, prognosis, and monitoring of disease and therapy. HTS is applied to screen millions of biological samples in search of potential biomarkers for earlier diagnosis of disease or the response to a particular drug. This directly comes into play in cancer, for instance, where earlier diagnosis and customized treatment would be huge benefit to the patients. With genomics and biomarker discovery being pushed to new extremes, the application of HTS technologies into these areas will further increase the accuracy and efficiency of drug discovery, ultimately leading to the development of targeted therapies and personalized medicine being streamlined.

Market Restraining Factors

Lack of Skilled Professionals in HTS Technologies

• Lack of skilled experts in High Throughput Screening (HTS) technologies is one of the most significant restraints that prevents the Global HTS Market from increasing. HTS systems, despite being very effective, are advanced and require good knowledge of automation, robotics, data analysis, and laboratory techniques. Specialized experts with complete know-how of HTS handling and interpretation need to undergo training and have mastery over the technical as well as scientific aspects of these systems. With the growing demand for HTS applications, especially in drug discovery and personalized medicine, the industry is confronted with a significant challenge concerning trained experts.
• The technological advancement of HTS, together with integration of leading-edge technologies such as machine learning and artificial intelligence, creates a demand for employees within the industry to have not only chemistry and biology skills but also knowledge in the management of advanced technology. Furthermore, management of massive datasets and identification of useful information demands qualifications and a lot of training. This lack of qualified personnel can retard the deployment and optimization of HTS systems, and ultimately erode drug discovery timelines. The industry thus needs to invest in training, education, and university collaborations to fill this skills gap and facilitate effective utilization of HTS technologies in research and development.

Segmentation Analysis

The market scope is segmented because of by Products and Services, by Technology, by Application, by End Use.

• By Products and Services

Based on the Products and Services of the market is segmented into Consumables (Reagents & Assay Kits, Laboratory Equipment), Instruments (Liquid Handling Systems, Detection Systems, Other Instruments), Services, Software.

Among all the product and service segments of the High Throughput Screening (HTS) market, the Consumables segment, reagents, assay kits, and lab equipment currently lead the market. Consumables top the market as they are the core element which enables HTS processes to occur. Reagents and assay kits are required in order to conduct high-throughput assays and screenings so that scientists can screen biological samples or compounds in bulk. These reagents are needed per cycle of screening and therefore form a repeat and high-demanding category in the HTS sector. In addition, laboratory supplies like tips, tubes, and microplates are essential for HTS operations and therefore contribute to this segment's growth.

The high proportion of consumables in the HTS market is, to a great extent, an indication of the growing demand for high-throughput screenings in drug discovery, biomarker identification, and diagnostics. As HTS is a key component of pharmaceutical research and biotechnology development, consumables are required at each phase of the work from target recognition and assay development to compound screening and lead optimization. With increasing drug discovery and disease research, the consumption of consumables does not increase, and thus this market segment continues to be a significant contributor.

• By Technology

Based on the Technology of the market is segmented into Cell-based Assays (Fluorometric Imaging Plate Reader Assays, Reporter based Assays, 3D - Cell Cultures, 2D - Cell Cultures, Reporter-based Assays, Perfusion Cell Culture), Lab-on-a-chip Technology (LOC), Label-free Technology, Ultra High Throughput Screening.

Among the technology segments included in the Global High Throughput Screening (HTS) Market, Cell-based Assays have dominated because of the vast use they have in disease modelling and drug discovery. This section has several types of assays including fluorometric imaging plate reader assays, reporter-based assays, and 2D and 3D cell cultures, and each of them plays its own role in HTS with the creation of a more biologically relevant screening environment. The cell-based assays are used by both the biopharmaceutical and biotech industry since they realistically reproduce the living organism's physiology and provide details regarding cellular response to drugs, toxicity, as well as mechanism of disease.

In this chapter, 3D cell cultures are increasingly gaining attention in the light of their superiority in mimicking in vivo situations compared to the conventional 2D culture. This has further improved the accuracy and pertinence of drug screening, establishing cell-based assays as an integral part of the HTS process. Second, cell-based assays are extremely flexible and are utilized in various areas of therapeutics like cancer studies, neurology, and immunology, extending their market dominance even further.

• Regional Snapshots

By region, Insights into the markets in North America, Europe, Asia-Pacific, Latin America and MEA are provided by the study. North America has led the Global High Throughput Screening (HTS) Market because of a host of important reasons such as its established healthcare infrastructure, excellent research and development capabilities, and home to the world's top pharmaceutical and biotechnology players. The United States has been a worldwide centre for pharmaceutical research, witnessing huge investments in drug discovery and cutting-edge technologies. The region's established regulatory environment, access to capital, and availability of internationally renowned research and educational institutions further enhance the demand for HTS technology. Moreover, growth in the adoption of personalized medicine and precision therapeutics in North America also increases the demand for enhanced efficiency and scalability in drug screening, which is facilitated by HTS. The reason why big biotechnology and healthcare companies are based in San Francisco, Boston, and New York is also a factor in determining market dynamics, hence making North America the market leader.

With regard to the highest growth rate, the Asia-Pacific will have the maximum growth rate for the HTS market. It is due to various reasons like the growth in the pharmaceutical and biotechnology industry in some of the nations such as China, India, and Japan. Higher incidence of chronic diseases, greater R&D expenditures, and higher numbers of contract research organizations (CROs) in the region are important drivers. In addition to this, comparatively low cost of operations in Asia-Pacific, growth in the development of healthcare infrastructure in the region, and growth of life science industries make the region a suitable location for the implementation of HTS technology. As more and more international companies are setting up their R&D and manufacturing hubs in the region, the Asia-Pacific market will become the fastest developing HTS market in the future years.

List of Companies Profiled

• Agilent Technologies, Inc.
• Danaher Corporation
• Thermo Fisher Scientific Inc.
• PerkinElmer Inc.
• Bio-Rad Laboratories, Inc.
• Aurora Biomed Inc.
• Tecan Trading AG
• Promega Corporation
• Charles River Laboratories.
• Creative Biolabs.

Key Industry Developments

• Enamine Ltd. and Metrion Biosciences Limited revealed in April 2024 that Enamine's compound libraries would be incorporated into HTS services of Metrion. This collaboration enhances Metrion's capabilities in drug discovery and development.
• To support further research and development, PerkinElmer announced the EnVison Nexus Multimode plate reader in February 2023.

Report Coverage

The report will cover the qualitative and quantitative data on the Global High Throughput Screening Market. The qualitative data includes latest trends, market players analysis, market drivers, market opportunity, and many others. Also, the report quantitative data includes market size for every region, country, and segments according to your requirements. We can also provide customize report in every industry vertical.

Report Scope and Segmentations

Regional Analysis:

Here are the regional snapshots for the High throughput screening market:

North America: North America is a significant market for HTS, driven by the presence of a large number of pharmaceutical and biotechnology companies, academic institutions, and contract research organizations. The region has a well-established research infrastructure and is at the forefront of technological advancements in HTS. The United States, in particular, is a major contributor to the HTS market in North America, with key research hubs and leading companies involved in drug discovery and development.

Europe: Europe is another prominent region in the HTS market, with a strong presence of pharmaceutical companies, academic research centers, and CROs. Countries like Germany, the United Kingdom, France, and Switzerland are notable contributors to the HTS market in Europe. The region has a robust regulatory environment, supportive funding initiatives, and collaborative research networks that drive HTS activities. Additionally, Europe has witnessed an increasing focus on personalized medicine and rare disease research, further fueling the demand for HTS technologies.

Asia Pacific: The Asia Pacific region is experiencing significant growth in the HTS market. Countries such as China, Japan, India, and South Korea are emerging as key players in HTS-driven research and drug discovery. Rapidly expanding pharmaceutical and biotechnology industries, increasing investments in research and development, and rising government initiatives to boost healthcare infrastructure are driving the growth of the HTS market in this region. Academic institutions and CROs are also playing a crucial role in advancing HTS capabilities in Asia Pacific.

Latin America: Latin America is witnessing steady growth in the HTS market. Countries like Brazil, Mexico, and Argentina are driving the market growth with their growing pharmaceutical industries and increasing focus on drug discovery and development. Academic and research institutions in the region are actively engaged in HTS-driven research. However, the market is still developing, and there is a need for increased awareness and investment in HTS technologies to fully unlock its potential.

Middle East and Africa: The HTS market in the Middle East and Africa is relatively nascent but growing. Countries like Israel, Saudi Arabia, and the United Arab Emirates are witnessing increased investment in research and development, including drug discovery efforts. Academic institutions and research centers are driving HTS activities in the region. However, there are infrastructure and funding challenges that need to be addressed to further develop the HTS market in this region.

High Throughput Screening Market Report is also available for below Regions and Country Please Ask for that

North America

• U.S.
• Canada

Europe

• Switzerland
• Belgium
• Germany
• France
• U.K.
• Italy
• Spain
• Sweden
• Netherland
• Turkey
• Rest of Europe

Asia-Pacific

• India
• Australia
• Philippines
• Singapore
• South Korea
• Japan
• China
• Malaysia
• Thailand
• Indonesia
• Rest Of APAC

Latin America

• Mexico
• Argentina
• Peru
• Colombia
• Brazil
• Rest of South America

Middle East and Africa

• Saudi Arabia
• UAE
• Egypt
• South Africa
• Rest Of MEA

Points Covered in the Report:

• The report will cover the qualitative and quantitative data on the high throughput screening market. The qualitative data includes latest trends, market player’s analysis, market drivers, market opportunity, and many others. Also, the report quantitative data includes market size for every region, country, and segments according to your requirements. We can also provide customize report in every industry vertical.
• The points that are discussed within the report are the major market players that are involved in the market such as market players, raw material suppliers, equipment suppliers, end users, traders, distributors and etc.
• The complete profile of the companies is mentioned. And the capacity, production, price, revenue, cost, gross, gross margin, sales volume, sales revenue, consumption, growth rate, import, export, supply, future strategies, and the technological developments that they are making are also included within the report. This report analysed 12 years data history and forecast.
• The growth factors of the market are discussed in detail wherein the different end users of the market are explained in detail.
• Data and information by market player, by region, by type, by application and etc., and custom research can be added according to specific requirements.
• The report contains the SWOT analysis of the market. Finally, the report contains the conclusion part where the opinions of the industrial experts are included.

Key Reasons to Purchase:

• To gain insightful analyses of the High Throughput Screening market and have comprehensive understanding of the global market and its commercial landscape.
• Assess the production processes, major issues, and solutions to mitigate the development risk.
• To understand the most affecting driving and restraining forces in the market and its impact in the global market.
• Learn about the High Throughput Screening market strategies that are being adopted by leading respective organizations.
• To understand the future outlook and prospects for the High Throughput Screening market. Besides the standard structure reports, we also provide custom research according to specific requirements.

Research Scope of High Throughput Screening Market:

• Historic year: 2019-2022
• Base year: 2023
• Forecast: 2024 to 2032
• Representation of Market revenue in $US Billion

High Throughput Screening Market Trends: Market key trends which include Increased Competition and Continuous Innovations Trends: