Market Overview

Global Single Cell Analysis Market size is estimated at USD 4.65 billion in 2024, and is expected to reach USD 8.63 billion by 2032, growing at a CAGR of 13.11% during the forecast period (2024-2032).

The reasons for this expansion are the increasing use of sequencing technology in drug research and disease diagnosis, its profitable expansion, developments in single-cell analysis and cell isolation technologies, and the increasing prevalence of cancer.

High-speed technological development has facilitated one to study the transcriptome and genome of an individual cell in depth. Single-cell analyses show different cell types to have different activities and ancestries, which determine each cell's reaction to alterations in the physiology of the host environment. Single-cell technology facilitates molecular route & process characterization as well as cellular heterogeneity measurement. Single-cell sequencing is advancing very fast, applied in immunology and oncology as well as a host of other uses. There are 22 phase-II clinical trials involving single-cell sequencing technology listed on Clinicaltrials.gov.

Single-cell analysis is required in precision medicine, where the treatment is customized according to the individual's unique characteristics. Clinicians can choose the best treatment for a patient based on profound insight into the cellular heterogeneity of a disease like cancer. A new study released in April of 2024 claims that researchers created an easy method to sort head and neck squamous cell cancer (HNSCC) based on B cells with single-cell analytical tools. The result of this trial will allow researchers to know how patients will do and react to immunotherapy. In addition, single-cell analysis enables scientists to understand how different cell types of the same tissue or organ react differently to medicines.

The market has grown exponentially with the lucrative and speedy advancement of sequencing technology. Understanding the intricacies of biology is now more and more dependent on single-cell analysis, an approach that measures the genomic, transcriptomic, proteomic, and metabolomic profiles of single cells. Thousands to millions of single cells can now be examined in a single experiment with much higher throughput using the available sequencing technology. This scale has provided access to new research findings and diagnostics, facilitating the development of the industry.

The advance in single-cell analysis and cell isolation technology has driven the expansion of the market. The sensitivity and resolution of single-cell analysis have been improved by new technologies, and low-abundance chemicals and rare cell types can be detected. Technical advancement has enlarged the scope of application for single-cell analysis and isolation; these include medicinal development, clinical diagnostics, and basic research. Also, cell biology research is applied in the incorporation of artificial intelligence in single-cell research. For example, NVIDIA and Deepcell, Inc. partnered in January 2024 to drive the application of generative artificial intelligence in single-cell research.

Market Drivers

Technological Advancements in Single-Cell Analysis Products

• On the market of single-cell analysis, companies are making increasingly more work to design affordable, innovative, and easy-to-use instruments. For instance, 10X Genomics brought to the light in February of 2024 the GEM-X technology that is the new version of its single-cell technical architecture and will support novel Chromium platform assays. GEM-X Single Cell Immune Profiling v3 and Chromium GEM-X Single Cell Gene Expression v4 are the first two to use 10X Genomics' new GEM-X technology architecture. Like this, Standard BioTools launched the Hyperion XTi Imaging System, a novel imaging platform, at the American Association for Cancer Research (AACR) conference in Orlando in April 2023.

Market Opportunity

High growth potential of single-cell sequencing

• Scientists can understand transcriptional unpredictability and cellular heterogeneity using single-cell sequencing (SCS). Advances in single-cell sequencing facilitate the better identification and investigation of microbial diversities in the environment, antibiotic drug-resistant strains, and infectious disease outbreaks. Since single-cell sequencing technology provides complete information about genetic mutations, companies are focusing on developing tools and materials compatible with single-cell sequencers. One of the most prominent firms in the market for single-cell analysis, US-based Illumina, Inc., offers integrated ultra-low-input and single-cell RNA sequencing protocols (utilizing the Nextera XT DNA Library Preparation Kit, Illumina sequencing platform, and the SMARTer Ultra Low Input RNA Kit from US-based Clontech Laboratories Inc.) that streamline the process as a whole, from biological interpretation to library preparation and data analysis. Several innovative SCS devices are expected to be created and launched in the market in the coming years, considering the enormous growth prospects of this sector.

Market Restraining Factors

High cost of single-cell analysis products

• There is extensive research in cell biology to develop new drugs, such as gene and stem cell therapies. For the purpose of obtaining consistent results, high-quality reagents, tools, and other products are employed in these research activities. The price of the instruments plays a significant role in the use of advanced single-cell analysis methods. High-content screening platforms, flow cytometers, and microfluidic devices with advanced features and functionalities are generally more costly. Due to their expensive development process, higher-generation instruments now come at a higher price than a previous generation. Thermo Fisher Scientific Inc., for instance, sells the ATTUNE NxT Flow Cytometer Invitrogen at USD 30,000 per unit. Likewise, Takara Bio Inc.'s SMARTer ICELL8 cx Single-Cell System is sold at USD 18,000 per unit.

Segmentation Analysis

The market scope is segmented because of by Product, by Application, by Workflow.

• By Product

Based on the Product of the market is segmented into Consumables, Instruments.

In 2023, the consumables segment commanded the largest revenue share of 55.1%, therefore leading the market. Market growth can be contributed to by the requirement for increased accuracy and extensive cellular analysis in research and clinical diagnostics, along with the increased demand for personalized medicine and biotechnology advances. Single-cell analysis consumables' market comprises several types of goods manufactured to simplify studying individual cells. These include materials like reagents, kits, microplates, and other tools used to undertake thorough analyses of single-cell behaviours, gene expression, and other important aspects of cell biology.

During the forecast period, the instruments segment is anticipated to grow at a significant CAGR. Patient assessment effectiveness has been enhanced by the application of smart technology, which has raised demand for single-cell technologies such as PCR and NGS. Moreover, the creation of integrated devices—such as laboratory equipment and in-patient monitoring and management devices—is enabling effective evaluation and administration of research labs and clinical trials, which is expected to fuel market growth.

• By Application

Based on the Application of the market is segmented into Cancer Immunology, Neurology, Stem cell, Non-invasive prenatal diagnosis, In-vitro fertilization Others.

The cancer segment held the majority share of 31.8% in 2023 and was thus the market leader. The growth potential of these technologies to have a substantial impact on cancer diagnosis and treatment makes this segment the leading growth driver. Single-cell analysis has been demonstrated to be useful for cancer cell diagnosis. These methods make it simple to ascertain genetic diversity in cell types, mutation rates, and cell growth conditions.

During the forecast period, the immunology segment will grow at the fastest pace. Scientists are able to describe comprehensively immune cell population heterogeneity as a result of single-cell analysis technologies. By investigating gene expression, epigenetic control, and protein expression at the single-cell level, scientists’ study molecular mechanisms underlying immune cell fate decisions, for instance, T-cell lineage commitment or B-cell differentiation. Moreover, single-cell analysis methods should investigate how the immune system reacts to different stimuli such as infection, vaccines, and cancer.

• Regional Snapshots

By region, Insights into the markets in North America, Europe, Asia-Pacific, Latin America and MEA are provided by the study. As per the latest analyses, the single-cell analysis market globally is dominated by North America. Its advanced research facilities, huge investments in the pharmaceutical and biotechnology sectors, and the presence of leading technological companies are the primary reasons for its dominance. The region's dominance is also supplemented by the high price of healthcare and the strong support offered for research and development. Single-cell technology innovation is largely propelled by the sheer number of academic and research organizations in the United States and Canada, with the latter's favourable research environment also playing a role.

The market of single-cell analysis is expected to grow at the fastest pace in Asia-Pacific. Huge R&D investments, increased healthcare expenses, and the rapid advancement of biotechnology in countries such as China, Japan, and India are the primary reasons for this growth. The area is expanding due to its augmented emphasis on individualised medicine and drug development coupled with enhanced investment by the public and private sector. The growth of the market in Asia-Pacific is also being fuelled by the proliferation of state-of-the-art research facilities and increased awareness of the clinical diagnostic applications of single-cell analysis.

List of Companies Profiled

• Thermo Fisher Scientific, Inc
• QIAGEN NV
• Bio-Rad Laboratories, Inc.
• Illumina, Inc.
• Merck KGaA
• Becton, Dickinson & Company (BD)
• Fluidigm Corporation (Standard BioTools Inc.)
• 10x Genomics, Inc.
• BGI
• Novogene Co, Ltd.

Key Industry Developments

In February 2024, as a move to diversify its products of single-cell technology, 10X Genomics recently introduced the launch of GEM-X, which are two single-cell gene assays namely Chromium Single Cell Immune Profiling 5'v3 and Chromium Single Cell Gene Expression 3'v4.

In February 2024, Takara Bio USA, Inc. launched two single-cell solutions, the Shasta Whole-Genome Amplification Kit and the Shasta Total RNA-Seq Kit.

In February 2024 Ann Arbour, USA-based Singleron Biotechnologies launched its laboratories. The company had aimed to deliver complete solutions starting from tissue dissociation to single-cell multi-omic analysis, automation instruments, single-cell reagent kits, and bioinformatics service.

In January 2024, Hamilton Ink, a robot development company, and BD announced an agreement that would support developing automated solutions to the requirements for single cell multiomics studies.

In January 2024, at the UK Festival of Genomics conference, Singleron Biotechnologies launched the AccuraSCOPE Single Cell Transcriptome and Genome Library Kit.  In its exclusive capability to profile the whole genome and the transcriptome in parallel, the kit offers researchers a precious tool for studying.

Report Coverage

The report will cover the qualitative and quantitative data on the Global Single Cell Analysis Market. The qualitative data includes latest trends, market players analysis, market drivers, market opportunity, and many others. Also, the report quantitative data includes market size for every region, country, and segments according to your requirements. We can also provide customize report in every industry vertical.

Report Scope and Segmentations:

Global Single-Cell Analysis Market Regional Analysis

North America accounted for the highest xx% market share in terms of revenue in the Single-Cell Analysis market and is expected to expand at a CAGR of xx% during the forecast period. This growth can be attributed to the growing adoption of Single-Cell Analysis. The market in APAC is expected to witness significant growth and is expected to register a CAGR of xx% over upcoming years, because of the presence of key Single-Cell Analysis companies in economies such as Japan and China.

The objective of the report is to present comprehensive analysis of Global Single-Cell Analysis Market including all the stakeholders of the industry. The past and current status of the industry with forecasted market size and trends are presented in the report with the analysis of complicated data in simple language.

Single-Cell Analysis Market Report is also available for below Regions and Country Please Ask for that

North America

• U.S
• Canada

Europe

• Switzerland
• Belgium
• Germany
• France
• U.K
• Italy
• Spain
• Sweden
• Netherland
• Turkey
• Rest of Europe

Asia-Pacific

• India
• Australia
• Philippines
• Singapore
• South Korea
• Japan
• China
• Malaysia
• Thailand
• Indonesia
• Rest Of APAC

Latin America

• Mexico
• Argentina
• Peru
• Colombia
• Brazil
• Rest of South America

Middle East and Africa

• Saudi Arabia
• UAE
• Egypt
• South Africa
• Rest Of MEA

Points Covered in the Report

• The points that are discussed within the report are the major market players that are involved in the market such as market players, raw material suppliers, equipment suppliers, end users, traders, distributors and etc.
• The complete profile of the companies is mentioned. And the capacity, production, price, revenue, cost, gross, gross margin, sales volume, sales revenue, consumption, growth rate, import, export, supply, future strategies, and the technological developments that they are making are also included within the report. This report analysed 5 years data history and forecast.
• The growth factors of the market are discussed in detail wherein the different end users of the market are explained in detail.
• Data and information by market player, by region, by type, by application and etc., and custom research can be added according to specific requirements.
• The report contains the SWOT analysis of the market. Finally, the report contains the conclusion part where the opinions of the industrial experts are included.

Key Questions

• How much the global Single-Cell Analysis Market valued?
• Which region has the largest share in 2024 for the global Single-Cell Analysis Market?
• What are the driving factors for the market?
• Which is the leading segment in the global market?
• What are the major players in the market?

Research Scope of Single-Cell Analysis Market

• Historic year: 2019- 2022
• Base year: 2023
• Forecast: 2024 to 2032
• Representation of Market revenue in USD Billion